The ORION OHS Knowledge Hub is a web-based technical infrastructure that facilitates networking of scientists within and across domains (animal health, food safety, and public helath) and institutions providing them with more effective means of collaboratively collecting, manipulating and managing data, as well as collaborative knowledge creation and transmission. Features of the ORION One Health Surveillance Knowledge Hub include e.g. Wiki’s, a shared calendar, a Tabular Data Manager, a Data Catalogue, a newsfeed, the developed web-based OH Knowledge Base, software code repositories etc.